VB中新建工程，添加一个按钮。

使用的时候，在IDE环境下F5运行和编译后运行就可以看到效果。

Option Explicit

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Private Declare Function GetModuleFileName Lib "kernel32" Alias _

??????? "GetModuleFileNameA" (ByVal hModule As Long, ByVal lpFileName As _

??????? String, ByVal nSize As Long) As Long

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Function IsRunUnderVB6() As Boolean

?Dim S As String

?Dim Length As Long

?Length = 256

?S = String(Length, 0)

?Call GetModuleFileName(0, S, Length)

?S = Left(S, InStr(S, Chr(0)) - 1)

?IsRunUnderVB6 = UCase(Right(S, 7)) = "VB6.EXE"

End Function

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Private Sub Command1_Click()

If IsRunUnderVB6 Then

MsgBox "调试"

Else

MsgBox "运行"

End If

End Sub

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看一看，比较简单